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In the latest centralized purchase of sitagliptin tablets, the price dropped to less than 20 cents per tablet, with a drop of over 90%. The reporter learned at the scene of the tenth batch of drug centralized purchase that more than 30 companies bid for sitagliptin, which is known as the largest variety in this centralized purchase, including Huahai Pharmaceutical, Kelun Pharmaceutical, Zhengda Tianqing, tonghua dongbao, Zhejiang Pharmaceutical, Jiudian Pharmaceutical, Shiyao Ouyi, Chenxin Pharmaceutical and many other companies. Judging from the bidding results, the lowest bid price among enterprises has dropped below 0.2 yuan per piece, which is more than 90% lower than the limit price. Statistics show that in 2023, the sales of this product in the terminals of public medical institutions in China exceeded 2 billion yuan, and the sales of Merck, the original research manufacturer, accounted for more than 90%, so there is a large room for generic drug substitution. The quotation of Meradong in this collection is about 7.37 yuan per piece. (science and technology innovation board Daily)EU finalizes new sanctions against Russia: strike against the "shadow fleet". According to a report on the website of German newspaper Sü ddeutsche Zeitung on December 11th, EU countries have reached an agreement on a new package of sanctions against Russia. Several diplomats told DPA that the new sanctions were aimed at strengthening the crackdown on the so-called "Russian shadow fleet" transporting oil and petroleum products. It is reported that more than 50 ships will be banned from entering EU ports. In addition, they can no longer get the services of EU enterprises. In June this year, the EU has taken preliminary measures to blacklist more than 20 Russian ships. It is reported that this is the 15th package of sanctions against Russia drawn up by the EU so far. The plan also stipulates that trade with more than 30 other business entities should be restricted, and the EU has determined that they should keep in touch with the Russian defense and security departments. In addition, the EU also plans to impose an entry ban and asset freeze on some individuals. According to the report, senior EU officials are pleased that member States have reached a consensus on this. Kaya Karas, the EU's High Representative for Foreign Affairs and Security Policy, said: "This will further weaken (Russian President) Putin's war machine." Roberta Metsola, Speaker of the European Parliament, said: "This sends another strong signal: our support for Ukraine will not weaken." The sanctions plan will be officially confirmed at the meeting of foreign ministers of member States in Brussels on the 16th, and then will be published in the official gazette of the European Union and come into effect. (Reference message)In 2023, the trade volume between the mainland and Macao increased by 4.3 times compared with that before the reunification. At the regular press conference held by the Ministry of Commerce today (12th), spokesman He Yadong introduced that by signing CEPA and its series of agreements, the mainland has fully liberalized its trade in goods and basically liberalized its trade in services. According to statistics, in 2023, the trade volume between the mainland and Macao was 3.84 billion US dollars, an increase of 4.3 times compared with that before the reunification. By October 2024, the mainland had absorbed a total of 23.93 billion US dollars of direct investment from Macao, and the mainland had invested 14.19 billion US dollars in Macao.

The attack on the headquarters of the Ministry of Refugees and Repatriation in Afghanistan killed four people. An official from the Ministry of Interior of the Afghan Interim Government said on the 11th that the suicide attack at the headquarters of the Ministry of Refugees and Repatriation that day killed four people and seriously injured four others. Mufti Abdul Martin Carney, spokesman of the Interior Ministry of the Afghan interim government, issued a statement on the 11th, confirming that Khalil Rahman Haqqani, Acting Minister of Refugee and Repatriation Affairs, was killed in the attack. Haqqani is one of the leading figures of the Taliban in Afghanistan, and also the uncle of sirajuddin Haqqani, Acting Minister of the Interior of the Afghan Interim Government. (Xinhua News Agency)Schlegel, Governor of the Swiss National Bank: It aims to stabilize the inflation rate at 0-2%. We can tolerate inflation temporarily below the target range of 0-2%.The Environmental Protection Department of the National Development and Reform Commission organized the liaison meeting of the coordination mechanism of cleaner production promotion departments in 2024. On the afternoon of December 10th, the Environmental Protection Department of the National Development and Reform Commission organized the liaison meeting of the coordination mechanism of cleaner production promotion departments in 2024 to sort out and summarize the latest progress, existing problems and difficulties in the implementation of cleaner production in 2024, study the key tasks in 2025, and promote the completion of the objectives and tasks of the Tenth Five-Year Plan.

In the latest centralized purchase of sitagliptin tablets, the price dropped to less than 20 cents per tablet, with a drop of over 90%. The reporter learned at the scene of the tenth batch of drug centralized purchase that more than 30 companies bid for sitagliptin, which is known as the largest variety in this centralized purchase, including Huahai Pharmaceutical, Kelun Pharmaceutical, Zhengda Tianqing, tonghua dongbao, Zhejiang Pharmaceutical, Jiudian Pharmaceutical, Shiyao Ouyi, Chenxin Pharmaceutical and many other companies. Judging from the bidding results, the lowest bid price among enterprises has dropped below 0.2 yuan per piece, which is more than 90% lower than the limit price. Statistics show that in 2023, the sales of this product in the terminals of public medical institutions in China exceeded 2 billion yuan, and the sales of Merck, the original research manufacturer, accounted for more than 90%, so there is a large room for generic drug substitution. The quotation of Meradong in this collection is about 7.37 yuan per piece. (science and technology innovation board Daily)Institution: A small interest rate cut by the European Central Bank may have a neutral impact on euro credit. Analysts of Yuxin Bank said in a report that the European Central Bank is expected to announce a 25 basis point interest rate cut tonight, which should have a neutral impact on euro-denominated credit. Analysts said that if the central bank cuts interest rates by 50 basis points further, it is unlikely to be beneficial to euro credit, because it will raise concerns about economic growth in the euro zone. According to the data of LSEG Refinitiv, the possibility that the market expects the European Central Bank to cut interest rates by 25 basis points is 83%, while the possibility of cutting interest rates by 50 basis points is 17%. Yuxin Bank said that as the European Central Bank continues to cut interest rates, the euro credit spread may fluctuate slightly or tighten slightly in the coming months.Ai Kelan: Liu Yi, the actual controller, intends to transfer 5% of the company's shares by agreement, with a total transaction price of 82.44 million yuan. Liu Yi, the controlling shareholder and actual controller, signed a share transfer agreement with Guangdong Nanchuan Private Equity Fund Management Co., Ltd., and Liu Yi intends to transfer 4 million unrestricted shares of the company (accounting for 5% of the company's total share capital) to Nanchuan Private Equity through agreement transfer. The transfer price is 20.61 yuan per share, and the total transaction price is 82.44 million yuan. This change in equity will not lead to changes in the controlling shareholder or actual controller of the company, and will not lead to changes in the control rights of listed companies.